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Barwon Health / Research

(03) 4215 0000

Intensive Care

Research is a pillar of intensive care medicine.  It is essential to inform how we best treat patients who are critically ill.  Conducting research in the ICU requires a particularly unique and considered approach, given patients are often unconscious and relatively high risk of dying in hospital.  Intensive care research has now matured to the extent that every critically patient is now afforded the opportunity to be part of a clinical trial.

Clinical trials currently underway at the Barwon Health ICU are investigating:

  • Type of fluid given after cardiac surgery
  • Medications to prevent bone loss
  • Choice of antibiotics and steroids for treating pneumonia
  • Medication to prevent gastric ulcers during critical illness
  • Mobilising critically ill patients early in their treatment
  • Protein concentration of nutrition
  • Optimal blood oxygen levels to target

There has also been a vast amount of ICU research work conducted during the COVID pandemic.  Our early adoption of adaptive trial designs ensured we were able to contribute to crucial studies on treating COVID patients admitted to ICU.

Barwon Health ICU is a member of the Australian and New Zealand Intensive Care Society – Clinical Trials Group (ANZICS-CTG), and also conducts research that ranges from multi-centre clinical trials to observational studies, single site and healthcare registry studies.

Please reach out to the ICU research team if interested in collaborating, or for any further information.

Research Areas

Collaborating Organisations

 Deakin University

Monash University  University of Adelaide 

 La Trobe University

Australia & New Zealand Intensive Care Society – Clinical Trials Group

College of Intensive Care Medicine

The George Institute for Global Health

Australia & New Zealand Intensive Care Society – Research Centre  


Research Team

Research staff

  • Matthew Maiden, Head of ICU Research
  • Michelle Horton, ICU Research Nurse
  • Jemma Trickey, ICU Research Nurse
  • Stephanie Pearce, ICU Research Nurse


Research Grants

  • MRFF - Bone Loss Prevention with Zoledronic Acid or Denosumab in Critically Ill Women: 2020-2025

Featured Publications

Long-Term Outcomes Following Severe Traumatic Brain Injury in Older Adults: A Registry-Based Cohort Study. (NOTE – Abstract only. Staff can request full text from Library). Maiden MJ, Cameron PA, Rosenfeld JV, Cooper DJ, McLellan S, Gabbe BJ. Am J Respir Crit Care Med. 2020 Jan;201(2):167-177. (Journal Impact Factor 16.5)

Structure and Function of the Kidney in Septic Shock: A Prospective Controlled Experimental Study. Maiden MJ, Otto S, Brealey JK, Finnis ME, Chapman MJ, Kuchel TR, Nash CH, Edwards J, Bellomo R. Am J Respir Crit Care Med. 2016 Sep;194(6):692-700. (Journal Impact Factor 13.2) 
Changes in Bone Mineral Density in the Year After Critical Illness. Orford NR, Lane SE, Bailey M, Pasco JA, Cattigan C, Elderkin T, Brennan-Olsen SL, Bellomo R, Cooper DJ, Kotowicz MA. Am J Respir Crit Care Med. 2016 Apr;193(7):736-44. (Journal Impact Factor 13.2) 
How doctors discuss major interventions with high risk patients: an observational study. Corke CF, Stow PJ, Green DT, Agar JW, Henry MJ. BMJ. 2005 Jan 22;330(7484):182. (Journal Impact Factor: 9.1)
Triiodothyronine Administration in a Model of Septic Shock: A Randomized Blinded Placebo-Controlled Trial. [NOTE - Full text for Barwon Health staff; public can view abstract]. Maiden MJ, Chapman MJ, Torpy DJ, Kuchel TR, Clarke IJ, Nash CH, Fraser JD, Ludbrook GL. Crit Care Med 2016 Jun;44(6):1153-1160. (Journal Impact Factor: 7.1) 
Haemoglobin concentration and volume of intravenous fluids in septic shock in the ARISE trial. Maiden MJ, Finnis ME, Peake S, McRae S, Delaney A, Bailey M, Bellomo R. Crit Care. 2018 May;22(1):118. (Journal Impact Factor:7.0) 
The association of time and medications with changes in bone mineral density in the 2 years after critical illness. Orford NR, Bailey M, Bellomo R, Pasco JA, Cattigan C, Elderkin T, Brennan-Olsen SL, Cooper DJ, Kotowicz MA. Crit Care. 2017 Mar;21(1):69. (Journal Impact Factor 6.4) 
Skeletal morbidity among survivors of critical illness. [NOTE - Full text for Barwon Health staff; public can view abstract]. Orford NR, Saunders K, Merriman E, Henry M, Pasco J, Stow P, Kotowicz M. Crit Care Med. 2011 Jun;39(6) 1295-300. (Journal Impact Factor 6.3) 

Obstetric admissions to intensive care units in Australia and New Zealand: a registry-based cohort study. [NOTE - Full text for Barwon Health staff; public can view abstract]. Maiden MJ, Finnis ME, Duke GJ, Huning E, Crozier T, Nguyen N, Biradar V, McArthur C, Pilcher D. BJOG. 2020 May 2. Ahead of Print. (Journal Impact Factor: 5.2)

The association between critical illness and changes in bone turnover in adults: a systematic review. Orford N, Cattigan C, Brennan SL, Kotowicz M, Pasco J, Cooper DJ. Osteoporos Int. 2014 Oct;25(10):2335-46. (Journal Impact Factor 4.2) 

Research Grants

  • MRFF - Bone Loss Prevention with Zoledronic Acid or Denosumab in Critically Ill Women: 2020-2025

Support Our Research

Participate in a Clinical Trial

To find out about clinical trials currently underway at Barwon Health, click here


Clinical trials require ongoing investment and there are several ways to support this amazing work.

You can make a donation today and contribute to an item on our research wish list, consider a bequest in your will, or establish a lasting legacy fund in your name. No matter what size, your philanthropic support with deliver an immediate impact.

To donate now or for more information and further discuss your support, please contact the Barwon Health Foundation.

Wish  List

  1. $2,000 will fund the purchase of IT software for data analysis and data presentation
  2. $5,000 will fund a -80 degrees freezer for storing biological samples
  3. $50,000 will fund the Project Coordinator who is essential to conducting of a planned Patient Related Outcomes Study.

All Publications


Last Modified: Tuesday, 16 August 2022

Research Lead

Matt Maiden.png

Dr Matthew Maiden, BMBS, PhD

Intensive Care Staff Specialist
Head of ICU Research
University Hospital Geelong, Level 4
Bellerine Street, Geelong 3220
Phone (03) 4215 1729