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Barwon Health / Research

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Cardiology

Since its establishment in June 2000, under the direction of Associate Professor John Amerena, the Geelong Cardiology Research Unit (CRU) has participated in numerous large scale global clinical trials in cardiovascular disease, and is recognised both nationally and internationally for conducting high quality clinical research and exceeding expected recruitment goals.

The CRU has been involved in approximately 200 pharmaceutical trials over the past 20 years. Up to 300 patients per year in the Geelong greater region are enrolled within our clinical trials at any one time. Their involvement provides local patients with the opportunity to gain access to medications that are not on the market as well as additional clinical monitoring and health care. The CRU has had a number of participants who have gone from study to study over the 20 year period due to their positive experience.

In addition, the CRU is an active member of the Melbourne Interventional Group (MIG) Registry.

The Cardiology Research Unit specialises in investigations into the following therapeutic areas:

  • Heart failure
  • Heart attack and unstable angina
  • High cholesterol
  • Atrial fibrillation / Atrial flutter
  • Peripheral Vascular Disease
  • Type 2 Diabetes
  • High blood pressure
  • Heart Failure
  • Obesity

The CRU has been involved in the development of a number of new therapies, treatment options and interventional procedures, which have now become standard of care for patients with cardiovascular disease.

A/Professor Amerena frequently performs the role of Australian National Coordinator for global clinical trials in cardiovascular disease, and holds positions on International Steering Committees/Endpoint committees overseeing the conduct of various clinical trials.

Our unit manager is the National Study Coordinator for Australia and sits on a global study coordinator steering committee.

Research Areas

Collaborating Organisations

Deakin University 

Monash University  Melbourne Interventional Group Registry 

 

Research Team

Research Staff

  • Associate Professor John Amerena - Director of Cardiology Research
  • Karen Fogarty - Research Manager
  • Anita Long - Research Manager (Daily Operations)
  • Susan Ryan - Study Coordinator
  • Donna Soraghan - Study Coordinator
  • Kate Sanders - Study Coordinator
  • Anne Welsh - Study Coordinator
  • Krystle Wilson- Study Coordinator

Research News

Featured Publications 

Hyponatraemia in heart failure. Tee SL, Sindone A, Roger S, Atherton J, Amerena J, D'Emden M, Erlich J, De Pasquale C. Intern Med J. 2020;50(6):659-66.

Vericiguat in patients with heart failure and reduced ejection fraction. [NOTE - Full text for Barwon Health staff; public can view abstract]. Armstrong PW, Pieske B, Anstrom KJ, Ezekowitz J, Hernandez AF, Butler J, Lam CSP, Ponikowski P, Voors AA, Jia G, et al. N Engl J Med. 2020;382(20):1883-93. 

Cited By

The effect of transitional care on 30-day outcomes in patients hospitalised with acute heart failure.  [NOTE - Full text for Barwon Health staff; public can view abstract]. Driscoll A, Dinh D, Prior D, Kaye D, Hare D, Neil C, Lockwood S, Brennan A, Lefkovits J, Carruthers H, et al. Heart Lung Circ. Ahead of print 2020.

Smartphone cardiac rehabilitation, assisted self-management versus usual care: Protocol for a multicenter randomized controlled trial to compare effects and costs among people with coronary heart disease. Rawstorn JC, Ball K, Oldenburg B, Chow CK, McNaughton SA, Lamb KE, Gao L, Moodie M, Amerena J, Nadurata V, et al. JMIR Res Protoc. 2020;9(1):e15022. 

Cited By   Citations in Context

Timing of staged nonculprit artery revascularization in patients with ST-segment elevation myocardial infarction: COMPLETE trial. [NOTE - Full text for Barwon Health staff; public can view abstract]. Wood DA, Cairns JA, Wang J, Mehran R, Storey RF, Nguyen H, Meeks B, Kunadian V, Tanguay JF, Kim HH, et al. J Am Coll Cardiol. 2019;74(22):2713-23.

Cited By

Angiotensin-neprilysin inhibition in heart failure with preserved ejection fraction. Solomon SD, McMurray JJV, Anand IS, Ge J, Lam CSP, Maggioni AP, Martinez F, Packer M, Pfeffer MA, Pieske B, et al. N Engl J Med. 2019;381(17):1609-20.

Cited By   Citations in Context

Complete revascularization with multivessel PCI for myocardial infarction. Mehta SR, Wood DA, Storey RF, Mehran R, Bainey KR, Nguyen H, Meeks B, Di Pasquale G, Lopez-Sendon J, Faxon DP, et al. N Engl J Med. 2019;381(15):1411-21.

Cited By   Citations in Context

Ticagrelor in patients with stable coronary disease and diabetes. Steg PG, Bhatt DL, Simon T, Fox K, Mehta SR, Harrington RA, Held C, Andersson M, Himmelmann A, Ridderstrale W, et al. N Engl J Med. 2019;381(14):1309-20.

Cited By   Citations in Context

Ticagrelor in patients with diabetes and stable coronary artery disease with a history of previous percutaneous coronary intervention (THEMIS-PCI): A phase 3, placebo-controlled, randomised trial. [NOTE - Full text for Barwon Health staff; public can view abstract].Bhatt DL, Steg PG, Mehta SR, Leiter LA, Simon T, Fox K, Held C, Andersson M, Himmelmann A, Ridderstrale W, et al. Lancet. 2019;394(10204):1169-80.

Cited By   Citations in Context

Effects of serelaxin in patients with acute heart failure. Metra M, Teerlink JR, Cotter G, Davison BA, Felker GM, Filippatos G, Greenberg BH, Pang PS, Ponikowski P, Voors AA, et al. N Engl J Med. 2019;381(8):716-26.

Cited By   Citations in Context

 

Support Our Research

Participate in a Clinical Trial

To find out about clinical trials currently underway at Barwon Health, click here.

Donate

Clinical trials require ongoing investment and there are several ways to support this amazing work,

You can make a donation today and contribute to an item on our research wish list, consider a bequest in your will, or establish a lasting legacy fund in your name. No matter what size, your philanthropic support with deliver an immediate impact.

To donate now or for more information and further discuss your support, please contact the Barwon Health Foundation.

Wish List

  1. $1000 - $5000 would fund a new ECG machine for the research unit.
  2. < $1000 would fund a much-needed set of electronic scales to weight patients registered in clinical trials up to 150kg.
  3. <$1000 will fund a printer to enable us to produce material for staff and patient education, as well as study updates to ensure our participants are well educated and well informed.

All Publications

Last Modified: Thursday, 06 August 2020

Research Leads

BHFJune0078

A/Prof John Amerena MB BS, FRACP, FCSANZ
Director of Cardiology

BHFJune0075

Karen Fogarty
Research Manager

Anita Long

 

Anita Long
Research Manager (Daily Operations)

University Hospital Geelong
Myers House, ground floor
Cnr Myers and Bellerine streets
Geelong VIC 3220
Ph (03) 4215 1033
[email protected]